Correlation Between Two-Hour Glucose Level and Blood Pressure in Nigerian Pregnant Women Attending Antenatal Metabolic Clinic in Jos University Teaching Hospital (JUTH)
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https://doi.org/10.61705/bbvdjx25Keywords:
Two-Hour Oral Glucose Tolerance, Diabetes, BP, Blood pressure, Jos, University teaching Hospital, AssessmentAbstract
Hypertension and diabetes mellitus are major global public health concerns that frequently coexist and contribute significantly to cardiovascular morbidity and mortality. Both conditions share common risk factors and often interact through complex metabolic pathways. The aim of this study was to assess the relationship between two-hour oral glucose tolerance and blood pressure parameters among patients attending Jos University Teaching Hospital.
A retrospective design was employed, reviewing hospital records from January 2021 to December 2022. The study population consisted of 171 adult patients who had complete records of systolic blood pressure (SBP), diastolic blood pressure (DBP), and two-hour OGTT results. Data were extracted using a structured checklist and analyzed with SPSS version 25. Descriptive statistics summarized baseline values, while Pearson correlation assessed relationships between OGTT results and blood pressure parameters. Chi-square analysis evaluated associations between glucose status and blood pressure categories.
The results showed that the mean systolic and diastolic blood pressure were 117.85 mmHg and 67.73 mmHg in 2021, and 111.80 mmHg and 69.50 mmHg in 2022, respectively. The overall mean two-hour glucose level was 6.57 mmol/L across both years. Correlation analysis indicated a weak, non-significant negative association between two-hour glucose and systolic BP (r = –0.044, p = 0.568) as well as diastolic BP (r = –0.104, p = 0.175). A strong positive correlation was observed between systolic and diastolic BP (r = 0.609, p < 0.001). Chi-square results showed no significant association between glucose status and blood pressure categories (χ² = –0.19, p = 0.80).
In conclusion, this study found no significant relationship between two-hour oral glucose tolerance and blood pressure parameters among patients in JUTH, although a strong positive correlation existed between systolic and diastolic pressures. These findings suggest that postprandial glucose regulation may not directly predict blood pressure in this population, underscoring the need for larger, prospective studies to better understand cardiometabolic interactions in Nigerian settings.
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