Association Between Cord Blood Lipid Profile and Neonatal Anthropometric Characteristics: A Comprehensive Analysis
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DOI:
https://doi.org/10.61705/h6svh577Keywords:
Cord blood , Lipid profile, Neonatal anthropometry, Birth weight, CholesterolAbstract
Context: In order to shed light on the function of lipid metabolism in fetal growth and development, the study sought to investigate the relationship between the lipid profile of cord blood and neonatal anthropometric traits.
Methods: A single tertiary care hospital hosted 300 infants for a cross-sectional study. The lipid profiles, which include "total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)," were examined in cord blood samples. Within 24 hours of birth, newborn anthropometric measurements were taken, including birth weight, length, and head circumference.
Findings: There were notable associations found between the lipid levels in cord blood and the anthropometric traits of newborns. Head circumference, length, and birth weight were positively correlated with TC and LDL-C levels, but negatively correlated with HDL-C levels. There was no discernible relationship between TG and the anthropometric traits of newborns. These relationships were validated by several linear regression models that controlled for potential confounding factors such as maternal age, gestational age, and maternal BMI.
Conclusion: The study's conclusion highlights the significance of lipid metabolism in fetal growth and development by showing a strong link between cord blood lipid levels and newborn anthropometric traits. Tracking the lipid profiles in cord blood may offer important insights into the health and development of the fetus, allowing for focused interventions to improve newborn outcomes and lower the chance of developing metabolic and cardiovascular problems later in life.
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