Correlation Between MRI-Based Radiological Features of Female Reproductive Organs and Blood Hormone Levels in Patients with PCOS: A Comprehensive Study
Abstract views: 490
/
PDF downloads: 93
DOI:
https://doi.org/10.61705/pv1jgq30Keywords:
luteinizing hormone, folicle-stimulating hormone, blood hormone levels, MRI, radiological features, polycystic ovary syndrome, androgen hormonesAbstract
Background: Women who are of reproductive age are frequently affected by PCOS, or polycystic ovarian syndrome, an endocrine condition. Clinical and biochemical factors, such as hormone abnormalities and polycystic ovarian morphology on ultrasound, are used to diagnose PCOS. Because magnetic resonance imaging (MRI) may provide extensive anatomical information on the ovaries and other pelvic tissues, it has become a viable imaging tool for the evaluation of PCOS.
Goal: Using MRI, examine the relationship between blood hormone levels and radiological characteristics of the female reproductive organs in patients complaining of PCOS.
Techniques: A total of 150 patients with PCOS diagnoses were drawn from departments of gynecology and endocrinology. Every patient had a pelvic MRI as well as a hormonal evaluation that included follicle-stimulating hormone (FSH), luteinizing hormone (LH), and androstenedione tests. Two skilled radiologists who were blinded to the clinical and hormonal information assessed the MRI scans. Ovarian volume, shape, the existence of ovarian cysts, the number and size of ovarian follicles, and stromal hyperplasia were among the radiological features evaluated. A statistical analysis was conducted to ascertain the relationship between blood hormone levels and radiographic findings.
Results: The most often seen radiological abnormalities in the research population were ovarian cysts, many tiny follicles, enlarged ovaries, and stromal hyperplasia. Radiological characteristics and levels of testosterone (r=0.65-0.72, p<0.001), LH (r=0.72-0.78, p<0.001), and FSH (r=0.60-0.70, p<0.001) were found to have significant positive relationships.
Conclusion: In conclusion, this study shows that blood hormone levels in individuals with PCOS complaints are significantly correlated with radiographic characteristics of the female reproductive organs. With its ability to provide detailed anatomical information and facilitate comprehension of the underlying hormonal abnormalities, MRI exhibits promise as an additional diagnostic technique in the diagnosis of PCOS.
Downloads
References
Palomba S, Santagni S, Falbo A, La Sala GB. Complications and challenges associated with polycystic ovary syndrome: current perspectives. Int J Womens Health. 2015 Sep 30;7:745-53. doi: 10.2147/IJWH.S70314. PMID: 26504346; PMCID: PMC4590139.
Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. Lancet. 2007 Sep 15;370(9588):685-97. doi: 10.1016/S0140-6736(07)61345-2. PMID: 17825644.
Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010 Oct 13;8:41. doi: 10.1186/1741-7015-8-41. PMID: 20939859; PMCID: PMC2975407.
Yildiz BO. Approach to the patient: contraception in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2015 Mar;100(3):794-802. doi: 10.1210/jc.2014-3761. PMID: 25405390.
Chen X, Ni R, Mo Y, Li L, Yang D, Li X, Ma B, Yang D. [Effect of lifestyle intervention on body weight and reproductive outcome in overweight and obese women with polycystic ovary syndrome]. Zhonghua Fu Chan Ke Za Zhi. 2015 May;50(5):375-9. Chinese. PMID: 26463577.
Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clin Epidemiol. 2014 Jul 22;6:1-13. doi: 10.2147/CLEP.S37559. PMID: 25093065; PMCID: PMC4128943.
Azziz R. Polycystic ovary syndrome. Obstet Gynecol. 2018 Sep;132(3):321-336. doi: 10.1097/AOG.0000000000002782. PMID: 30095790.
Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016 Jul;106(1):6-15. doi: 10.1016/j.fertnstert.2016.05.003. Epub 2016 May 30. PMID: 27262475.
Palomba S, de Wilde MA, Falbo A, Koster MP, La Sala GB, Fauser BC. Pregnancy complications in women with polycystic ovary syndrome. Hum Reprod Update. 2015 Sep-Oct;21(5):575-92. doi: 10.1093/humupd/dmv029. Epub 2015 Jul 5. PMID: 26141281.
Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ; International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 2018 Sep 1;33(9):1602-1618. doi: 10.1093/humrep/dey256. PMID: 30052961.
Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, Welt CK; Endocrine Society. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2013 Dec;98(12):4565-92. doi: 10.1210/jc.2013-2350. PMID: 24151290; PMCID: PMC5393198.
Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, Lobo R, Norman RJ, Talbott E, Dumesic DA. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab. 2010 Feb;95(5):2038-49. doi: 10.1210/jc.2009-2724. PMID: 20375205; PMCID: PMC2869542.
Additional Files
Published
Issue
Section
License
Copyright (c) 2025 International Journal of Medical Research

This work is licensed under a Creative Commons Attribution 4.0 International License.
All papers should be submitted electronically. All submitted manuscripts must be original work that is not under submission at another journal or under consideration for publication in another form, such as a monograph or chapter of a book. Authors of submitted papers are obligated not to submit their paper for publication elsewhere until an editorial decision is rendered on their submission. Further, authors of accepted papers are prohibited from publishing the results in other publications that appear before the paper is published in the Journal unless they receive approval for doing so from the Editor-In-Chief.
IJMR open access articles are licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. This license lets the audience to give appropriate credit, provide a link to the license, and indicate if changes were made and if they remix, transform, or build upon the material, they must distribute contributions under the same license as the original.
