Role of Probiotics in Enhancing the Effects of Physiotherapy in Patients with Metabolic Syndrome


Abstract views: 100 / PDF downloads: 101

Authors

  • Maman Paul Assistant Professor, Department of Physiotherapy, Guru Nanak Dev University, Amritsar-143005, Punjab, India Author

DOI:

https://doi.org/10.61705/f3n1sh13

Abstract

Metabolic syndrome (MetS) refers to a constellation of metabolic disturbances such as central obesity, insulin resistance, dyslipidemia, and hypertension that together heighten the risk of developing cardiovascular disease and type 2 diabetes. Physiotherapy, particularly exercise-based interventions, is pivotal in improving metabolic health and physical function in MetS patients. Recent evidence suggests that gut microbiota modulation through probiotics may complement physiotherapeutic approaches by improving metabolic control, inflammation, and muscle function. Probiotic bacteria are live microorganisms incorporated into foods that confer health benefits to the host. They are commonly present in fermented products such as yogurt, kefir, sauerkraut, kimchi, and soybean-based foods like miso and natto. Probiotics exert a wide range of beneficial effects, including the modulation of gastrointestinal function and related disorders, enhancement of immune responses, and improvement of conditions such as hyperlipidemia, hypertension, and allergies. This article reviews the mechanisms through which probiotics enhance the outcomes of physiotherapy in metabolic syndrome, emphasizing their role in systemic inflammation reduction, insulin sensitivity improvement, and overall success of the interventions.

Downloads

Download data is not yet available.

References

Gavrilova NB, Chernopolskaya NL, Bukharev AG, Pogorelova NA, Dolmatova IA, Salekhov SA. Current trend in the development of biotechnology of a specialized dairy product for nutrition of athletes. IOP Conf. Ser.: Earth Environ. Sci. 2020;613:012036.

Gleeson M, Bishop NC, Oliveira M, Tauler P. Daily probiotic's (Lactobacillus casei Shirota) reduction of infection incidence in athletes. Int J Sport Nutr Exerc Metab. 2011 Feb;21(1):55-64. doi: 10.1123/ijsnem.21.1.55.

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F. Diagnosis and management of the metabolic syndrome: American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112(17):2735–52.

Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, Morelli L, Canani RB, Flint HJ, Salminen S, et al. Expert consensus document. The international scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014;11:506–14. https://doi.org/10.1038/nrgastro.2014.66.

Ibrahim NS, Muhamad AS, Ooi FK, Meor-Osman J, Chen CK. The effects of combined probiotic ingestion and circuit training on muscular strength and power and cytokine responses in young males. Appl Physiol Nutr Metab. 2018 Feb;43(2):180-186.

Jäger R, Mohr AE, Pugh JN. Recent advances in clinical probiotic research for sport. Curr Opin Clin Nutr Metab Care. 2020 Nov;23(6):428-436. doi: 10.1097/MCO.0000000000000686. PMID: 32769404; PMCID: PMC7575027.

Marttinen M, Ala-Jaakkola R, Laitila A, Lehtinen MJ. Gut Microbiota, Probiotics and Physical Performance in Athletes and Physically Active Individuals. Nutrients. 2020 Sep 25;12(10):2936. doi: 10.3390/nu12102936. PMID: 32992765; PMCID: PMC7599951.

Maughan RJ, Burke LM, Dvorak J, Larson-Meyer DE, Peeling P, Phillips SM, Rawson ES, Walsh NP, Garthe I, Geyer H, et al. IOC consensus statement: dietary supplements and the high-performance athlete. Br J Sports Med. 2018;52:439–55. https://doi.org/10.1136/bjsports-2018-099027.

Morales MIA, Pacheco DV, Morales BJA. Influence of physical activity and nutritional habits on the risk of metabolic syndrome. Enfermería Global.2016; 15: 222–234.

Pane M, Amoruso A, Deidda F, Graziano T, Allesina S, Mogna L. Gut Microbiota, Probiotics, and Sport: From Clinical Evidence to Agonistic Performance. J Clin Gastroenterol. 2018 Nov/Dec;52 Suppl 1:S46-S49. doi: 10.1097/MCG.0000000000001058.

Pugh JN, Wagenmakers AJM, Doran DA, Fleming SC, Fielding BA, Morton JP, Close GL. Probiotic supplementation increases carbohydrate metabolism in trained male cyclists: a randomized, double-blind, placebo-controlled crossover trial. Am J Physiol Endocrinol Metab. 2020 Apr 1;318(4):E504-E513. doi: 10.1152/ajpendo.00452.2019. Epub 2020 Feb 18. PMID: 32069071.

Rowland I, Capurso L, Collins K, Cummings J, Delzenne N, Goulet O, Guarner F, Marteau P, Meier R. Current level of consensus on probiotic science--report of an expert meeting--London, 23 November 2009. Gut Microbes. 2010;1:436–9. https://doi.org/10.4161/gmic.1.6.13610.

Shaw G, Slater G, Burke LM. Changes in the Supplementation Practices of Elite Australian Swimmers Over 11 Years. Int J Sport Nutr Exerc Metab. 2016 Dec;26(6):565-571. doi: 10.1123/ijsnem.2016-0060.

Torres S, Fabersani E, Marquez A, Gauffin-Cano P. Adipose tissue inflammation and metabolic syndrome: The proactive role of probiotics. Eur J Nutr. 2019;58(1):27–43. doi: 10.1007/s00394-018-1790-2.

Zeman M, Valášková L. Application of physiotherapy in persons at risk of metabolic syndrome development. Neuroendocrinol Lett. 2017;38(7):484–7.

Additional Files

Published

2025-12-27

Issue

Section

Articles

How to Cite

1.
Role of Probiotics in Enhancing the Effects of Physiotherapy in Patients with Metabolic Syndrome. International Journal of Medical Research [Internet]. 2025 Dec. 27 [cited 2026 Oct. 23];1(6):17-24. Available from: https://ijmr.online/index.php/ijmr/article/view/116