FORMULATION AND EVALUATION OF RAPID DISSOLVING TABLET - REVIEW


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Authors

  • Priyanka V. Gawali SGSPS Institute of Pharmacy, Kaulkhed, Akola Author
  • Ankita S. Bethe SGSPS Institute of Pharmacy, Kaulkhed, Akola Author
  • Vaibhav S. Jadhav SGSPS Institute of Pharmacy, Kaulkhed, Akola Author
  • Dr. Balmukund R. Rathi SGSPS Institute of Pharmacy, Kaulkhed, Akola Author

DOI:

https://doi.org/10.61705/m8bnnf55

Keywords:

Rapid dissolving tablets, buccal disintegration, formulation, superdisintegrants, quality control tests

Abstract

In the current scientific environment, medication delivery technology is fiercely competitive and developing quickly due to rising demand. One such novel and distinctive drug delivery method that is quickly garnering significant attention in the realm of rapid dissolving technology research is the rapid dissolving tablet (RDT).Due to the large variety of medications that may be taken orally, this is the fastest and safest method of drug administration. Researchers have recently created Rapid dissolving tablets (RDTS), which dissolve or disintegrate quickly in saliva in the mouth without the need for water. Some tablets are known as genuine fast-dissolving tablets because they are designed to dissolve in saliva very quickly—in just a few seconds. Because RDTs include ingredients that accelerate the pace at which tablets disintegrate in the oral cavity, it is more appropriate to refer to them as fast disintegrating tablets. It can take them up to a minute to dissolve entirely.RDTs Superdisintegrants are added to formulations to speed up a tablet’s buccal disintegration.  This analysis outlines the many benefits, restrictions, and ideal qualities of formulation elements, use of super-disintegrate, technology used for RDTs and unique hole technology, medication ingredients for Rapid dissolving tablets, quality control tests , commercial formulations, and Patented drugs.

References

Ramakant Joshi , Navneet Garud and Wasim Akram , “Fast dissolving tablets : review Article” IJPSR (2020), Volume 11, Issue 4.

R.D.Rahane,Dr Punit R. Runchh,“A review on fast dissolving tablet”,Journal of Drug Delivery & Therapeutics. 2018; 8(5):50-55.

Kushagra Khanna, Gauravi Xavier, Suresh Kumar Joshi, Aashish Patel, Sakshum Khanna, Vipin and Bhawna Goel ,“Fast Dissolving Tablets- A Novel Approach”,Int. J. Pharm. Res. Allied Sci., 2016, 5(2):311-322.

Mangesh Machhindranath Satpute, Nagesh Shivaji Tour,“ Formulation and in vitro Evaluation of fast dissolving tablets of metoprolol tartrate”,Brazilian Journal of Pharmaceutical Sciences, vol. 49, n. 4, oct./dec., 2013.

CH. Jyothi, K. Akhil Kumar, M. Mamatha, N. Mamatha, G. Soujanya and Dr. K. Hemamalini,“FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ZIDOVUDINE USING SUBLIMATION TECHNIQUE”,World Journal of Pharmaceutical Research,Vol 7, Issue 13, 2018.

CH. Jyothi, K. Akhil Kumar, M. Mamatha, N. Mamatha, G. Soujanya and Dr. K. Hemamalini,“FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ZIDOVUDINE USING SUBLIMATION TECHNIQUE”,World Journal of Pharmaceutical Research,Vol 7, Issue 13, 2018.

Garima Yadav, Anupriya Kapoor and Shilpi Bhargava,“FAST DISSOLVING TABLETS RECENT ADVANTAGES: A REVIEW”,IJPSR (2012), Vol. 3, Issue 03.

ASHISH MASIH, AMAR KUMAR, SHIVAM SINGH, AJAY KUMAR TIWARI,“FAST DISSOLVING TABLETS: A REVIEW ”,Int J Curr Pharm Res, Vol 9, Issue 2, 8-18.

Priyanka Nagar, Kusum Singh, Iti Chauhan, Madhu Verma, Mohd Yasir, Azad Khan, Rajat Sharma and Nandini Gupta ,“Orally disintegrating tablets : formulation, preparation Techniques and evaluation”,Journal of Applied Pharmaceutical Science 01 (04); 2011: 35-45.

Debjit Bhowmik, Chiranjib.B, Krishnakanth, Pankaj, R.Margret Chandira,“Fast Dissolving Tablet: An Overview ”,Journal of Chemical and Pharmaceutical Research, 2009, 1(1): 163-177 .

PREETI, VIJAY AGARWAL, ABHINAV AGARWAL,“AN OVERVIEW ON MOUTH DISSOLVING TABLET: FROM MANUFACTURING AND PATENTED TECHNIQUE TO QUALITY CONTROL TEST”, Asian J Pharm Clin Res, Vol 15, Issue 11, 2022, 7-13.

Keshari Roshan , M. Bharkatiya, Rathore K.S, Shyama S. Kumar, Gajaram Sirvi,

somani Neelam Bhupal Nobels,“FAST DISOLVING TABLET DRUG DELIVERY SYSTEM- AN OVERVIEW”,Keshari, et al. Int J Pharm 2015; 5(2): 577-589.

Basu B, Abhishek B, Sagar M, Vora V, Devraj Bhatt, Abhay D. Formulation and Evaluation of fast dissolving tablets of cinnarizine using super disintegrant blends and Subliming material. Journal of Advanced Pharmaceutical Technology & Research. 2011; 2(4): 266–273.

Prakash Ved, S. Maan, Deepika, Shiv Kumar Yadav, Hemlata, Vikas J. Fast Disintegrating tablets: Opportunity in drug delivery system. Journal of Advanced Pharmaceutical Technology & Research. 2011; 2(4): 223–235.

Bahrainian S, Abbaspour M, Kouchak M, Taghavi M. P. A Review on Fast

Dissolving Systems: From Tablets to Nanofibers. Jundishapur J Nat Pharm Prod. 2017; 12(2): 34267.

Neeta, Dureja Harish, Bhagwan Shiv, Seema, Dahiya JyoJyoti,“ Fast dissolving tablets:An overview”,Novel Science International Journal of Pharmaceutical Science (2012), 1(5):228-232 228 .

V.Dinesh kumar , Ira Sharma and Vipin Sharma,“A comprehensive review on fast Dissolving tablet Technology ”,Journal of Applied Pharmaceutical Science 01 (05); 2011: 50-58.

Kuchekar BS, Atul, Badhan C, Mahajan H S, Mouth dissolving tablets: A novel drug Delivery system, Pharma Times, 35, 2003, 7-9.

Kuno Y, Kojima M, Ando S, Nakagami H,“Evaluation of rapidly disintegrating tablets Manufactured by phase transition of sugar alcohols”,Journal of Controlled Release ,2005; 105(1, suppl 2): 16-22.

Yu DG, Shen XX, Han J, Zhu LM,Branford-White C, Li XY, Yang XL,“ Oral Fast-Dissolving DDD Fabricated Using 3DP”, Bioinformatics and Biomedical

Engineering. The 2nd International Conference 2008; 1602–605.

Ito A, Sugihara M. Development of oral dosage forms for elderly patients: use of agar as Base of rapidly disintegrating oral tablets. Chem Pharm. Bull. 1996; 44(11):2132-136.

Gauri, S., Kumar, G., Fast Dissolving Drug Delivery and its Technologies,The Pharma Innovation,2012,1(2),34-39.

Deshmukh, V. N., Mouth Dissolving Drug Delivery System: A Review,Int J. Of PharmTech Research,2012,4(1),412-421.

Sharma R, Rajput M, Prakash P, Sharma S. Fast dissolving drug delivery system: a Review. Int Res J Pharm 2011;2:21-9.

Ahet Smita S,Saudagar R B ,Shinde Mayuri S,“ Fast Dissolving Tablets – A review ”,Int J Curr Pharm Res, Vol 10, Issue 2, 5-12.

Kumar AH, Kavitha K, Kumar SA, Kumar MR, Singh SD. Novel approach of bilayer tablet Technology-a review. Int J Pharm Chem Biol Sci 2013;3:887-93.

Deepak Sharma,“ Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate for Respiratory Disorders ”, ISRN Pharmaceutics,vol 2013,pg 8.

B. Senthilnathan and A. Rupenagunta, “Formulation development and evaluation of Venlafaxine hydrochloride orodispersible tablets,” International Journal of Pharmaceutical Sciences and Research, vol. 2, no. 4, pp. 913–921, 2011.

Alok Kumar Gupta, Anuj Mittal and Prof. K. K. Jha,“Fast Dissolving Tablet- A Review”,THE PHARMA INNOVATION, Vol. 1 No. 1 2012.

S.Muralidhar, T.V.Narayana,Ch.S.Phani Kumar ,Mahajan Anil Arun ,“Formulation And Evaluation Of Fast Dissolving Tablets By Addition Of Different Concentrations Of Superdisintegrant And By Effervescent Technology”,Int J. Pharm. Drug. Anal, Vol: 7, Issue: 1, 2019; 1 – 10.

Md.Nehal Siddiqui, Garima Garg, Pramod Kumar Sharma,“ FAST DISSOLVING TABLETS: PREPARATION, CHARACTERIZATION AND EVALUATION: ANOVERVIEW”, International Journal of Pharmaceutical Sciences Review and Research,Volume 4, Issue 2, September – October 2010; Article 015.

Chang RK, Guo X, Burnside BA, Couch RA. Fast dissolving tablets. Pharm Tech, 2000; 24(6):52-58.

Jaysweh J Harani, Dhaval A Rathod, Kantilal R Vadila, Orally disintegrating tablets, A Review, Tropial Journal of Pharm.Sciences, 2009, 8(2), 161-172.

Noushin Bolourchian, Mohammad Mehdi Mahboobian, and Simin Dadashzadeh. “The Effect of PEG molecular weights on dissolution behavior of Simvastatin in solid Dispersions.” Iranian journal of pharmaceutical research: IJPR 12, no. Suppl (2013): 11.

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Published

2024-05-02

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1.
FORMULATION AND EVALUATION OF RAPID DISSOLVING TABLET - REVIEW. International Journal of Medical Research [Internet]. 2024 May 2 [cited 2024 Nov. 23];3(2):20-33. Available from: https://ijmr.online/index.php/ijmr/article/view/63