EFFECTS OF CONSUMPTION OF MATURED AND UNRIPE Carica papaya ON MALONDIALDEHYDE, PACKED CELL VOLUME AND ORGAN FUNCTIONS IN RATS
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https://doi.org/10.61705/cj8t9z56Keywords:
Carica papaya, pawpaw, rats, oxidative stress, renal functions in rats, kidney enzyme functions in ratsAbstract
Carica papaya, is a member of the Caricaceae family, widely known as pawpaw in Nigeria and is widely used in traditional medicine to treat various ailments. However, there is limited information about the effects of consuming both ripe and unripe pawpaw fruit. This study aims to evaluate the impact of unripe Carica papaya consumption on MDA levels, PCV, and liver and kidney enzyme functions in rats. The study involved feeding three groups of six albino rats with a diet containing 20% unripe papaya mixed in grower's marsh, while a control group received standard feed for 28 days, with body weight monitored throughout. After the feeding period, samples were collected and analyzed using standard procedures. The results indicated a significant difference (p>0.05) increase in weight across all groups. Proximate analysis of test samples ranged as follows. Carbohydrate content 21. 20 ± 0.92 to 20.15±0.27, dry matter content from 33.39 ±5.45 to 25.52±7.85, protein content from 1.91±0.04 to 2.19±0.02, Fat content from 0.99±0.03 to 1.30±0.03, fibre content from 11.77±0.03 to 12.61±0.02, moisture content 7.61±0,85 to 8.15±0.17 and ash content from 7.51±0.02 to 8.53±0.03 respectively. Among the different group of feeds administered to rats, the peeled samples showed significant ability to reduce both ALT/AST activity as well as urea concentration. While the steamed unpeeled sample, showed significant ability to reduce creatinine and MDA concentration along with GGT activity. Conclusively, the results obtained from the various assays, implies that both the peeled and steamed sample of mature unripe Carica papaya has been found to be effective in reducing oxidative stress and promoting improvement in such conditions. of both hepatic and renal functions in rats.
References
Arinathan, B. (2003).Chemical composition of certain tribal pulses in South India Int J Food SciNutr 54: 209-217.
Awolola, T. S., Oduola, A. O., Obansa, J. B., Chukwurar, N. J., & Unyimadu, J. P. (2007). Anopheles gambiae ss breeding in polluted water bodies in urban Lagos, southwestern Nigeria. Journal of vector borne diseases, 44(4), 241.
DeFoliart, G. R. (1992). Insects as human food: Gene DeFoliart discusses some nutritional and economic aspects. Crop protection, 11(5), 395-399.
Dick Gross .(2003). "Papaya". A tantalizing taste of the Tropics. Maricopa County Master Gardner Volunteer information, University of Arizona Cooperative Extensive.www.papayaMaricopa-hort@ag.arizo.edu refrevw win?
Imaga,N.O.A., Gbenle,G.O., Okochi, V.I., Akanbi S.O., Edeoghon, S.O., Oigbochie, V, Kehinde, M.O. and Bamiro, S.B (2009) Antisickling property of C. papaya leaf extracts Africa.J.of Biochemistry Research. Vol.3 (4) Pp. 102-106.
Josiah, S., Nwangwa,S.C., Usunobun, U., Npya, H. and Adejumo, B.1. (2011). Protective effect of ethanolic extract of unripe pulp of carica papaya against potassium bromate induced tissue damaged in Wistar rats. Current Research Journal Biological Science 3 (6) 567-600.
Mæhre, H. K., Dalheim, L., Edvinsen, G. K., Elvevoll, E. O., & Jensen, I. J. (2018). Protein determination—method matters. Foods, 7(1), 5.
Mitra, S., & Rennie, J. (2017). Neonatal jaundice: aetiology, diagnosis and treatment. British Journal of Hospital Medicine, 78(12), 699-704.
Oduola, T., Adeniyi, F.A.A., Ogunyemi, E.O., Bello, 1.5, Idowu, T.O. and Subair, H.G.(2007) Toxicity Studies on unripe Carica papaya aqueous extract, biochemical and hematological effects in wistar rats. J. of Med. Plants, Research Vol 1pp.001-004.
Puwastien, P.B., Burlingame, M., Rarocngwichit, M. and Sungpuag, P. (2000). ASEAN Food Composition Tables of Nutrition, Mahidol University, Thailand.
Rasool, A., Shah, F. A., & Islam, J. U. (2020). Customer engagement in the digital age: A review and research agenda. Current Opinion in Psychology, 36, 96-100.
Rex Immanuel, R., & Ganapathy, M. (2020). Ameliorative effect of multipurpose tree species (MPT’S) on coastal degraded soils. Plant Archives, 20(Sup 1), 801-807.Josiah et al., 2011
Tietz, F. (1999). Thermal expansion of SOFC materials. Ionics, 5, 129-139.
Watson, J. (1997). The theory of human caring: Retrospective and prospective. Nursing science quarterly, 10(1), 49-52.
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